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This new edition reflects the remarkable clinical and scientific advances in bone and soft tissue reconstruction since publication of the first edition of this award-winning book 7 years ago. Highly potent recombinant growth factors are now widely available, and numerous chapters describe and provide cases illustrating how to incorporate these protein therapeutics into clinical practice. The reader will find information about the basic principles of tissue engineering, use of growth factors in orthopedics, and potential applications of gene therapy in dentistry. The book also features chapters on periodontal regeneration and localized implant site development. A section on applications for craniofacial reconstruction describes procedures for use of growth factors in the treatment of defects. The final section addresses orthopedic indications for tissue engineering. An invaluable, up-to-date resource for practitioners wanting to integrate tissue engineering into their clinical practice, researchers seeking inspiration for new directions, and those new to this fascinating field. Contents: Part 1: Principles of Tissue Engineering - Protein Theraputics and Bone Healing-- Jeffrey O. Hollinger, Charles Hart, Reinhard Gruber, Bruce Doll
- Basic Principles of Tissue Engineering-- Myron Spector
- Advances in Gene Therapy for Periodontal Bioengineering-- William V. Giannobile
- Application of Tissue Engineering Principles to Clinical Practice-- Robert E. Marx
Part 2: Periodontal Regeneration and Localized Implant Site Development - Treatment of Advanced Periodontal Defects Using Bioactive Therapies-- Myron Nevins, Samuel E. Lynch, Emil G. Cappetta
- Use of rhPDGF to Improve Bone and Periodontal Regeneration-- Samuel E. Lynch, Myron Nevins
- Soft Tissue Engineering Applications in Dentistry-- Michael K. McGuire
- Site Development for Implant Placement: Regenerative and Esthetic Techniques in Oral Plastic Surgery-- Marc Nevins, James T. Mellonig
- Use of PRP in Oral and Maxillofacial Surgery and Periodontology-- Robert E. Marx
- Minimally Invasive Strategies for Vertical Ridge Augmentation-- Massimo Simion, Isabella Rocchietta
- rhBMP-2: Biology and Applications in Oral and Maxillofacial Surgery and Periodontics-- John M. Wozney, Ulf M. E. Wikesjö
- Osseous Regeneration with rhBMP-2-- Joseph P. Fiorellini, N. Guzin Uzel, Julio Sekler
- Bone Augmentation of the Maxillary Sinus Floor with rhBMP-2-- R. Gilbert Triplett
- Alveolar Distraction Osteogenesis and Tissue Engineering-- Ole T. Jensen, Zvi Laster, Hideharu Hibi, Yoichi Yamada, Minoru Ueda
- Dentoalveolar Modification with an Osteoperiosteal Flap and rhPDGF-BB Ole T. Jensen
Part 3: Craniofacial Reconstruction - Clinical Applications of rhBMP-2-- Alan S. Herford, Philip J. Boyne
- Craniofacial Osseous Reconstruction with rhBMP-2 in the Growing Patient-- Ember L. Ewings, Michael H. Carstens
- Tissue Engineering Strategies in the Treatment of TMDs-- Mary Beth Schmidt, Leslie Robin Halpern
Part 4: Orthopedic Indications - Application of rhPDGF-BB in Foot and Ankle Fusion Procedures-- Tim Daniels
- The Role of Growth Factors in Tendon Healing-- Joshua C. Nickols, Joshua Dines
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