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Endodontic Microbiology, Second Edition presents a comprehensive reference to the microbiology, pathogenesis, management, and healing of endodontic pathosis, emphasizing the importance of biological sciences in understanding and managing endodontic disease and its interaction with systemic health. The book has been thoroughly updated to reflect new studies and advances in knowledge, particularly in the areas of next generation sequencing, microbial virulence, and the relationship of endodontic pathosis and systemic diseases. Written by the leading educators and researchers in the field, Endodontic Microbiology provides a state-of-the-art, contemporary resource for understanding and eradicating intracanal infection. Chapters thoroughly cover the growing body of knowledge about endodontic microbiology, including molecular analysis, periapical microbiology, and virulence. The science is situated within the clinical context, providing a complete resource for understanding and treating endodontic disease. Endodontic Microbiology is an essential reference for predoctoral and postgraduate endodontics students, practicing endodontists, and researchers in this area. Key features - Provides a major revision to the first book to focus on the problems related to microbes in the root canal and periapical tissues
- Updates current knowledge in endodontic pathosis, especially regarding next generation sequencing and microbial virulence
- Presents useful diagrams, images, radiographs, and annotated histological images to illustrate the concepts
- Emphasizes the importance of biological science in understanding and managing endodontic disease
- Includes contributions from the leading researchers and educators in the field
Author Information Ashraf F. Fouad, DDS, MS, is Freedland Distinguished Professor and Chair in the Department of Endodontics at the University of North Carolina, Chapel Hill, North Carolina, USA. Table of Contents - Contributors ix
- Preface xi
- Preface to the First Edition xiii
- Microbial Perspectives in the Twenty-First Century 1
—William Wade - Diagnosis, Epidemiology, and Global Impact of Endodontic Infections 11
—Dag Ørstavik - Microbiology of Dental Caries and Dentinal Tubule Infection 25Robert M. Love and Anne C.R. Tanner
- Culture-Based Analysis of Endodontic Infections 51
—Gunnar Dahlén - Molecular Analysis of Endodontic Infections 81
—José F. Siqueira, Jr, and Isabela N. Rôças - Extraradicular Endodontic Infections 129
—Brenda P. F. A. Gomes and Ericka T. Pinheiro - Virulence of Endodontic Bacterial Pathogens 149
—Christine Sedgley - Viruses in Endodontic Pathosis 179
—Mohamed Sabeti - Fungi in Endodontic Infections 197
—Bilge Hakan Sen and B. Güniz Baksi - Severe Head and Neck Infections 231Jaime S. Brahim and Robert A. Ord
- Endodontic Infections and Pain 251
—Anibal Diogenes and Ken M. Hargreaves - Systemic Antibiotics in Endodontic Infections 269
—Ashraf F. Fouad - Topical Antimicrobials in Endodontics 287
—Anil Kishen - Endodontic Infections in Incompletely Developed Teeth 311
—George T.J. Huang, Domenico Ricucci, and Louis M. Lin - Prognosis of Healing in Treated Teeth with Endodontic Infections 341
—Shimon Friedman - Endodontic Infections and Systemic Disease 385
—Ashraf F. Fouad
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