This new edition of Immunology: A Short Course:

• Has been fully revised and updated, with a brand new art program to help reinforce learning
• Includes a new chapter on Innate Immunity to reflect the growth in knowledge in this area
• Highlights important therapeutic successes resulting from targeted antibody therapies
• Includes end of chapter summaries and review questions, a companion website at www.wileyimmunology.com/coico featuring interactive flashcards, USMLE-style interactive MCQs, figures as PowerPoint slides, and case-based material to help understand clinical applications

Author Information

Richard Coico, SUNY Downstate College of Medicine, Brooklyn, New York

Geoffrey Sunshine, Heath Effects Institute, and Tufts University School of Medicine, Boston, Massachusetts

Table of Contents:

1. OVERVIEW OF THE IMMUNE SYSTEM, 1
2. INNATE IMMUNITY, 11
3. ADAPTIVE IMMUNITY, 26
4. IMMUNOGENS AND ANTIGENS, 35
5. ANTIBODY STRUCTURE AND FUNCTION, 47
6. ANTIGEN-ANTIBODY INTERACTIONS, IMMUNE ASSAYS, AND EXPERIMENTAL SYSTEMS, 67
7. THE GENETIC BASIS OF ANTIBODY STRUCTURE, 88
8. BIOLOGY OF THE B LYMPHOCYTE, 100
9. HOW T CELLS RECOGNIZE ANTIGEN: THE ROLE OF THE MAJOR HISTOCOMPATIBILITY COMPLEX, 117
10. BIOLOGY OF THE T LYMPHOCYTE, 137 CONTENTS IN BRIEF
11. ACTIVATION AND FUNCTION OF T CELLS, 153
12. CYTOKINES, 176
13. TOLERANCE AND AUTOIMMUNITY, 194
14. COMPLEMENT, 217
15. HYPERSENSITIVITY: TYPE I, 233
16. HYPERSENSITIVITY: TYPES II AND III, 249
17. HYPERSENSITIVITY: TYPE IV, 259
18. IMMUNODEFICIENCY DISORDERS AND NEOPLASIAS OF THE LYMPHOID SYSTEM, 268
19. TRANSPLANTATION, 298
20. TUMOR IMMUNOLOGY, 312
21. RESISTANCE AND IMMUNIZATION TO INFECTIOUS DISEASES, 32